Book cheap flights from Santo Domingo to Panama City from £343
Santo Domingo
Panama City
Sun, 22 Dec
SDQ - PTY
Sun, 05 Jan
PTY - SDQ
£457
£446
Prime price per passenger
Santo Domingo
Panama City
Fri, 17 Jan
SDQ - PTY
£407
£402
Prime price per passenger
Santo Domingo
Panama City
Fri, 10 Jan
SDQ - PTY
Wed, 15 Jan
PTY - SDQ
£349
£343
Prime price per passenger
Santo Domingo
Panama City
Mon, 30 Dec
SDQ - PTY
Sun, 05 Jan
PTY - SDQ
£567
£557
Prime price per passenger
Santo Domingo
Panama City
Sat, 04 Jan
SDQ - PTY
Sat, 11 Jan
PTY - SDQ
£566
£556
Prime price per passenger
Santo Domingo
Panama City
Thu, 09 Jan
SDQ - PTY
Sat, 11 Jan
PTY - SDQ
£577
£568
Prime price per passenger
Booking a flight from Santo Domingo to Panama City
Booking your flight through eDreams is simple. Just enter Santo Domingo and Panama City as your departure and destination cities, choose the dates of your trip, and search through the available options. Our search engine will find the best deals from thousands of routes and flight combinations.
We also offer a ‘Smart Choice’ option, by which we highlight the most competitive flights at the top of the search results. You can also apply filters to view only flights to Panama City from your preferred airlines.
Changes to the price of your flights during your booking
Flight fares are set up using a complex pricing algorithm based on demand and seat availability. As a result, the cost of your flight may vary during your booking process. To secure the best price for your flight to Panama City, make sure you book as soon as you find a flight ticket that suits your pocket.
eDreams Prime members discounts
As an eDreams Prime member, you can access exclusive deals and save hundreds on flights, hotels, and car hires, along with many other benefits. Join the world’s largest travel membership community and discover all the advantages of eDreams Prime.
Last-minute bookings with eDreams
eDreams also offers last-minute flights at competitive prices. While these may be more expensive, we provide a range of options to suit your needs. Keep in mind, though, that last-minute prices can be higher, particularly during peak travel season. Being flexible with your travel dates can increase your chances of finding better deals.
Checking in before your flight
Online check-in usually opens 24 to 48 hours before the departure time. Once your booking with eDreams is completed, we’ll email you one week before your day of departure with instructions on how to check in for your flight.
Best season to travel from Santo Domingo to Panama City
Panama offers endless possibilities, from its rich gastronomy to its diverse culture and stunning nature. The best time to travel depends on your preferences and availability. Always consider the climate, peak tourist season, and the type of experience you’re seeking.
Expect larger crowds during peak season, but you'll also enjoy a lively atmosphere and more cultural and touristic offerings. Travelling off-season usually means fewer crowds, lower prices on flights and accommodations, and a more authentic glimpse into local life. While some outdoor activities may be limited due to the weather conditions, popular attractions will likely be less crowded, allowing for a more immersive experience.
Flight Time
4 h and 8 m
Flights from Santo Domingo and Panama City last around 4 h and 8 m, although this flight time may also depend on other factors.
Cheapest flight
£343
The cheapest price available for flights from Santo Domingo to Panama City that have been booked by our customers in the last 72 hours
Airport of Departure
Las Americas
You will depart from Las Americas when flying from Santo Domingo to Panama City
Airport of Arrival
Tocumen International Airport
Outbound flights from Santo Domingo to Panama City arrive at Tocumen International Airport